Phakathi kwe-80 vs phakathi kwe-20: Iiyantlukwano eziphambili kunye nendlela yokukhetha kwiSicelo sakho

Phakathi kwama-20 kunye nama-80 omabiniPolyoxyethylene Sorbitan Fatty Acid Esters (TWEEN), i-nonionic surfactants esetyenziswa ngokuqhelekileyo ekunakekeleni komntu, amayeza, ukutya kunye nokusetyenziswa kwezoshishino. Zikwabizwa ngokuba yi-TW20 kunye ne-TW80 kwamanye amashishini. Ngenxa yokuba amagama afanayo, abathengi abaninzi babuza umbuzo ofanayo: yintoni umehluko phakathi kwe-Tween 20 kunye ne-Tween 80, kwaye ingaba zinokusetyenziswa ngokutshintshisanayo?

Ngokwesiqhelo, i-Tween 20 kunye ne-Tween 80 zihlala zikhethwa kwiinkqubo ezahlukeneyo zokuqulunqa. Umahluko ophambili uvela kwisiseko sabo se-asidi enamafutha. Phakathi kwe-20 (i-Polysorbate 20) ivela kwi-lauric acid enexabiso le-HLB ye-16.7, ngelixa i-Tween 80 (i-Polysorbate 80) ivela kwi-oleic acid enexabiso le-HLB le-15.0. Nangona zombini ziyi-surfactants ye-nonionic enyibilikayo emanzini, lo mahluko wesakhiwo uchaphazela ukuziphatha kwabo kwe-emulsification, ukuhambelana kwe-oyile kunye nokuzinza kokwakheka.

Phakathi kwe-20: Ingcono kwiiNkqubo zokuSekwa ​​kwamanzi kunye neMild Emulsification

Ixabiso eliphezulu le-HLB le-Tween 20 lenza ukuba i-hydrophilic ngakumbi, yingakho ikhethwa ngokuqhelekileyo kwiinkqubo ezifuna ukuchithwa kwamanzi okulungileyo kunye ne-emulsification epholileyo. Usetyenziso oluqhelekileyo lubandakanya:

• Iimveliso zokhathalelo lomntu ezifana nezicoci zobuso, iitoni kunye namanzi e-micellar, apho kufuneka i-solubilization ethambileyo yevumba elimnandi okanye izithako zeoyile.
• Imixube yezithambiso ifuna izithambiso ezirhabaxa kancinci
• Amalungiselelo amayeza aquka izisombululo zomlomo kunye neengqungquthela zezihloko
• Izicelo zeLabhoratri ezifana ne-protein solubilization kunye nemidiya yenkcubeko yeeseli

Phakathi kwe-80: Kungcono kwi-Oil-Containing kunye ne-Emulsion Systems

Ixabiso le-HLB ephantsi kancinci kunye nesiseko se-oleic ye-oleic ye-Tween 80 yenza ukuba ifaneleke ngakumbi kwiinkqubo ezinomxholo ophezulu we-oyile, okanye apho izithako ezisebenzayo ezinyibilikayo kufuneka zihlakazwe okanye zixutywe. Isetyenziswa ngokubanzi kwi:

• Ii-emulsions zokuthambisa ezifana neekhrimu kunye neloshini apho i-oyile ezinzileyo emanzini kufuneka i-emulsification.
• Iimveliso zamachiza ezibandakanya ukuxutywa kwe-injection, i-emulsions yomlomo kunye ne-vitamin oil dispersions
• Iimveliso zesondlo ezifana ne-fat-soluble vitamin emulsification kwiziselo kunye nezongezelelo
• Usetyenziso lwemizi-mveliso kubandakanya i-lubricant emulsification kunye nempahla encedisayo

Unokukhetha njani phakathi kwe-20 kunye nePhakathi kwe-80

Ukhetho akufanele lusekelwe kwigama lemveliso kuphela. Izinto eziphambili ekufuneka ziqwalaselwe zibandakanya iimfuno ze-HLB, uhlobo lwesigaba se-oyile kunye nokugxininiswa, ukuhambelana namanye ama-surfactants okanye izithako ezisebenzayo, umgangatho kunye neemfuno zamaxwebhu, kunye nokuzinza kwemveliso phantsi kobushushu, i-pH kunye neemeko zokugcina.

Ekubeni abaninzi abathengi bathelekisa la mabanga mabini ngexesha lokukhethwa kwemveliso, iDotachem ilungiselele itafile yokuthelekisa elula yokubhekisela.

Kwiimeko ezininzi, uvavanyo oluncinci luyacetyiswa ngaphambi kokuqinisekisa ibakala lokugqibela, njengoko ukusebenza kunokwahluka ngokuxhomekeka kwiimeko zesicelo zangempela.

Kumaqela okuthengwa kwempahla, kubalulekile kwakhona ukuqinisekisa ukucaciswa kwemveliso, ukhetho lokupakisha, ixesha lokukhokela kunye namaxwebhu afunekayo obugcisa ngaphambi kokufaka umyalelo. Oku kubaluleke ngakumbi kubathengi kukhathalelo lomntu, amayeza kunye nemveliso ejolise kumazwe angaphandle.

I-Dotachem ngumthengisi osekelwe e-China wemveliso ye-Polysorbate equka i-Tween 20 (i-Polysorbate 20) kunye ne-Tween 80 (i-Polysorbate 80) yokunyamekela komntu, izicelo zamachiza kunye nezoshishino. Abathengi basenokuba nomdla kwiimveliso ezinxulumene ezifanaIISorbitan Monolaurate(Isithuba),Polyethylene Glycol(PEG),Ipropylene Glycol(PG) kunye nezinye ii-surfactants ezikhethekileyo.

QhagamshelanaI-Dotachem yenkcazo yemveliso, ukhetho lokupakisha okanye inkxaso yekowuteshini ye-Tween series surfactants.